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RNA Ladders

Common RNA ladder products and features include:

  • Thermo Fisher Scientific RiboRuler RNA Ladders: Chromatography-purified RNA transcripts. Available in low (100–1000 bases) and high range (200–6000 bases). Ideal for sizing and approximate in-gel quantification as the concentration of each band is predetermined.
  • Thermo Fisher Scientific Millennium Markers: Evenly spaced markers (0.5 to 9 kb) optimized for denaturing gels and constructing highly accurate standard curves for mRNA determination.
  • Bio-Rad RNA Ladders: Broad-range ssRNA standards (typically 50–9000 bases) designed for Northern blotting and verification of RNA transcript size following in vitro transcription.
Product Meta

RNA ladders are sets of single-stranded RNA fragments of known sizes used as molecular weight standards in gel electrophoresis. By running them alongside unknown RNA samples, researchers can accurately determine the size, quantity, and integrity of their RNA transcripts on native or denaturing agarose gels.